Caspase-4 Substrate LEVD-AFC

SKU
C-2242
  • Formula:C32H40F3N5O11
  • MW:727.5
  • Appearance:Liquid
  • Purity:99% by HPLC
Product Name Qty
Caspase-4 Substrate LEVD-AFC
200 assays
$290.47
Caspase-4 Substrate LEVD-AFC
1000 assays
$620.78

Ready-to-use fluorometric substrate for caspase-4 and related caspases that recognize the amino acid sequence LEVD. Caspase-4 and related caspase activity can be quantified by fluorescent detection of free AFC after cleavage from the peptide substrate LEVD-AFC at Ex. = 400 nm and Em. = 505 nm, using a fluorometer or multi-well fluorescence plate reader. Alternatively, a shift in fluorescence from blue to green upon cleavage can be visualized using a hand-held long-UV lamp.

More Information
Alternate Name/Synonyms
Ac-LEVD-AFC, Caspase-4 Substrate, Fluorogenic
SKU
C-2242
Chemical Name
Ac-LEVD-AFC, Caspase-4 Substrate, Fluorogenic
Chemical Formula
C32H40F3N5O11
Molecular Weight
727.5
Appearance
Liquid
Purity
99% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Fluorometric substrate for caspase-4 and related caspases that recognize the amino acid sequence LEVD
MDL NUMBER
MFCD01862605
CHEMACX
X1340772-0
INCHI
InChI=1S/C32H40F3N5O11/c1-14(2)10-21(36-16(5)41)30(49)38-20(8-9-24(42)43)28(47)40-27(15(3)4)31(50)39-22(13-25(44)45)29(48)37-17-6-7-18-19(32(33,34)35)12-26(46)51-23(18)11-17/h6-7,11-12,14-15,20-22,27H,8-10,13H2,1-5H3,(H,36,41)(H,37,48)(H,38,49)(H,39,50)(H,40,47)(H,42,43)(H,44,45)
SMILES
CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C
Peptide sequence
AC-LEU-GLU-VAL-ASP-AFC
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
GHS PICTOGRAMS
HandlingProtect from light and moisture
UN #'SNot Applicable
Packing GroupNot Applicable
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