Caspase-6 Substrate VEID-AFC

SKU
C-2248
  • Formula:C32H40F3N5O11
  • MW:727.7
  • Appearance:Liquid
  • Purity:95% by HPLC
Product Name Qty
Caspase-6 Substrate VEID-AFC
200 assays
$290.47
Caspase-6 Substrate VEID-AFC
1000 assays
$620.78

Ready-to-use fluorometric substrate for caspase-6 and related caspases that recognize the amino acid sequence VEID. Caspase-6 and related caspase activity can be quantified by fluorescent detection of free AFC after cleavage from the peptide substrate VEID-AFC at Ex/Em = 400/505, using a fluorometer or multi-well fluorescence plate reader. Alternatively, a shift in fluorescence from blue to green upon cleavage can be visualized, using a hand-held long-UV lamp. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large amount of caspase-6 assays. Cell Lysis Buffer (Cat. #1067-100, -400) and 2X Reaction Buffer (Cat. #1068-20, -80) for caspase assays are also available separately.

More Information
Alternate Name/Synonyms
Ac-VEID-AFC, Caspase-6 Substrate, Fluorogenic
SKU
C-2248
Chemical Name
Ac-VEID-AFC, Caspase-6 Substrate, Fluorogenic
Chemical Formula
C32H40F3N5O11
Molecular Weight
727.7
Appearance
Liquid
Purity
95% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Fluorometric substrate for caspase-6 and related caspases that recognize the amino acid sequence VEID
MDL NUMBER
MFCD07780888
CHEMACX
X1340847-2
INCHI
InChI=1S/C32H40F3N5O11/c1-6-15(4)27(40-28(47)20(9-10-23(42)43)38-30(49)26(14(2)3)36-16(5)41)31(50)39-21(13-24(44)45)29(48)37-17-7-8-18-19(32(33,34)35)12-25(46)51-22(18)11-17/h7-8,11-12,14-15,20-21,26-27H,6,9-10,13H2,1-5H3,(H,36,41)(H,37,48)(H,38,49)(H,39,50)(H,40,47)(H,42,43)(H,44,45)
SMILES
CCC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C
Peptide sequence
AC-VAL-GLU-ILE-ASP-AFC
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
GHS PICTOGRAMS
HandlingProtect from light and moisture
UN #'SNot Applicable
Packing GroupNot Applicable
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