Caspase-8 Inhibitor Z-IETD-FMK

SKU
C-2253
  • Formula:C30H43FN4O11
  • MW:654.7
  • Appearance:Liquid
  • Purity:>99% by HPLC
Product Name Qty
Caspase-8 Inhibitor Z-IETD-FMK
20 ul (10mM)
$136.69

A synthetic peptide that irreversibly inhibits FLICE and related protease/caspase activity and blocks apoptosis. IETD is the specific recognition sequence found in CPP32 proenzyme. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups.)

More Information
Alternate Name/Synonyms
Z-IETD-FMK, Caspase-8 Inhibitor (fluoromethylketone)
SKU
C-2253
Chemical Name
Z-IETD-FMK, Caspase-8 Inhibitor (fluoromethylketone)
Chemical Formula
C30H43FN4O11
Molecular Weight
654.7
Appearance
Liquid
Purity
>99% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Not Available
MDL NUMBER
MFCD08461000
CHEMACX
X1206331-9
INCHI
InChI=1S/C30H43FN4O11/c1-6-17(2)25(35-30(43)46-16-19-10-8-7-9-11-19)28(41)32-20(12-13-23(38)44-4)27(40)34-26(18(3)36)29(42)33-21(22(37)15-31)14-24(39)45-5/h7-11,17-18,20-21,25-26,36H,6,12-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,40)(H,35,43)/t17-,18+,20-,21-,25-,26-/m0/s1
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCc1ccccc1
Peptide sequence
Z-ILE-GLU(O-ME)-THR-ASP(O-ME) FLUOROMETHYL KETONE
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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