Caspase-9 inhibitor Z-LEHD-FMK

SKU
C-2256
  • Formula:C32H43FN6O10
  • MW:690.7
  • Appearance:Liquid
  • Purity:98% by HPLC
Product Name Qty
Caspase-9 inhibitor Z-LEHD-FMK
20 ul (10mM)
$136.69

A synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

More Information
Alternate Name/Synonyms
Caspase-9/Mch6 Inhibitor,Z-LEHD-FMK, Caspase-9 (fluoromethylketone)
SKU
C-2256
Chemical Name
Sequence: Z-Leu-Glu(OMe)-His-Asp(OMe)-FMK (FMK, fluoromethyl ketone).
Chemical Formula
C32H43FN6O10
Molecular Weight
690.7
Appearance
Liquid
Purity
98% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Not Available
MDL NUMBER
MFCD01862609
CHEMACX
X1341207-2
INCHI
InChI=1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)
SMILES
CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
Peptide sequence
Z-LEU-GLU(OME)-HIS-ASP(OME)-FMK .TFA
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Certificate of Analysis 1
Certificate of Analysis 2
GHS PICTOGRAMS
HandlingProtect from light and moisture
UN #'SNot Applicable
Packing GroupNot Applicable
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