Caspase Substrate (Chromogenic), Ac-DEVD-pNA

SKU
C-1129
  • Formula:C26H34N6O13
  • MW:638.6
  • Appearance:White Lyophilized Powder
  • Purity:98%

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Substrate for caspase-3. Also reported subtrate for caspase 1, 4 and 7. ; max. of pNA is 400nm.

More Information
Alternate Name/Synonyms
Ac-Asp-Glu-Val-Asp-pNA, Ac-DEVD-pNA, Caspase Substrate (Chromogenic), Caspase -1, Caspase -4, Caspase -7
SKU
C-1129
Chemical Name
Ac-Asp-Glu-Val-Asp-pNA
Chemical Formula
C26H34N6O13
Molecular Weight
638.6
Appearance
White Lyophilized Powder
Purity
98%
Solubility
Water
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
A colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases
MDL NUMBER
MFCD00792707
CHEMACX
X1218447-3
INCHI
InChI=1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,22H,8-11H2,1-3H3,(H,27,33)(H,28,41)(H,29,42)(H,30,43)(H,31,40)(H,34,35)(H,36,37)(H,38,39)/t16-,17-,18-,22-/m0/s1
SMILES
O=C(Nc1ccc(cc1)[N+]([O-])=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(=O)O)CCC(=O)O)C(C)C)CC(=O)O
Peptide sequence
AC-ASP-GLU-VAL-ASP-PNA
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial
Citations
Bleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells Ognoon Mungunsukh, Autumn J. Griffin, Young H. Lee, and Regina M. Day Am J Physiol Lung Cell Mol Physiol, May 2010; 298: L696 - L703.
Citations_Hyperlink
http://ajplung.physiology.org/cgi/reprint/298/5/L696
Certificate of Analysis 1
Handling Store in Tightly Sealed Vial
UN #'S Not Applicable
Packing Group Not Applicable
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