Caspase Substrate (Fluorogenic), Ac-WEHD-AMC

SKU
C-1043
  • Formula:C38H40N8O11
  • MW:784.8
  • Appearance:White Lyophilized Powder
  • Purity:99% (HPLC)
Product Name Qty
Caspase Substrate (Fluorogenic), Ac-WEHD-AMC
5 mg
$159.47
Caspase Substrate (Fluorogenic), Ac-WEHD-AMC
1 mg
$56.95

Fluorogenic substrate for caspase-1 and 5. Also a substrate for caspase-4. This fluorogenic caspase-1 substrate with an optimal tetrapeptide sequence is cleaved 50-fold more efficiently than Ac-YVAD-AMC (Prod. No.C-1009). Peptide Content: 70-90%

More Information
Alternate Name/Synonyms
Ac-Trp-Glu-His-Asp-AMC, Ac-WEHD-AMCCaspase-1 Substrate (Fluorogenic), Caspase-5 Substrate (Fluorogenic), Caspase-4
SKU
C-1043
Chemical Name
Ac-Trp-Glu-His-Asp-AMC
Chemical Formula
C38H40N8O11
Molecular Weight
784.8
Appearance
White Lyophilized Powder
Purity
99% (HPLC)
Solubility
DMSO (50 mM)
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Fluorogenic substrate for caspase-1 and 5
MDL NUMBER
MFCD01318829
CHEMACX
X1218192-3
INCHI
InChI=1S/C38H40N8O11/c1-19-11-34(52)57-31-14-22(7-8-24(19)31)43-36(54)30(15-33(50)51)46-38(56)29(13-23-17-39-18-41-23)45-35(53)27(9-10-32(48)49)44-37(55)28(42-20(2)47)12-21-16-40-26-6-4-3-5-25(21)26/h3-8,11,14,16-18,27-30,40H,9-10,12-13,15H2,1-2H3,(H,39,41)(H,42,47)(H,43,54)(H,44,55)(H,45,53)(H,46,56)(H,48,49)(H,50,51)/t27-,28-,29-,30-/m1/s1
SMILES
Cc1cc(=O)oc2c1ccc(c2)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@@H](Cc3c[nH]cn3)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](Cc4c[nH]c5c4cccc5)NC(=O)C
Peptide sequence
AC-TRP-GLU-HIS-ASP-MCA
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Store in Tightly Sealed Vial
UN #'S Not Applicable
Packing Group Not Applicable
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