Cefpodoxime (free acid)

SKU
C-1475
  • CAS:80210-62-4
  • Formula:C15H17N5O6S2
  • MW:427.45 Da
  • Appearance:Off-white to yellowish powder
  • Purity:≥95.0%

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Product Name Qty
Cefpodoxime (free acid)
1 g
$220.07
Cefpodoxime (free acid)
5 g
$549.64

Description

Cefpodoxime (free acid), antibiotic is active against most Gram-negative organisms, with exception Pseudomonas aeruginos. Cefpodoxime is used in antibiotic susceptibility testing for Neisseria Gonorrhea. Cefpodoxime is both a sensitive and specific indicator of an extended-spectrum β-lactamases in K. pneumoniae

 

More Information
Alternate Name/Synonyms
Cefpodoxima; Cefpodoximum
SKU
C-1475
CAS #
80210-62-4
Chemical Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula
C15H17N5O6S2
Molecular Weight
427.45 Da
Appearance
Off-white to yellowish powder
Purity
≥95.0%
Solubility
Soluble in DMSO
Melting Point
200-202°C
Preparation
N/A
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Infectious Diseases
USE
Cefpodoxime is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms. Notable exceptions include Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. It is commonly used to treat acute otitis media, pharyngitis, sinusitis, and gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment.
Merck Index
N/A
MDL NUMBER
MFCD00864906
CHEMACX
X1004423-0
INCHI
InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
SMILES
COCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/c3csc(n3)N)SC1)C(=O)O
Peptide sequence
Not Applicable
RTECS
XI0367365
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Avoid breathing fumes. Use only with adequate ventilation. Wear suitable protective clothing, gloves, and eye/face protection. Keep away from sources of ignition. Minimize dust generation and accumulation. Keep container tightly closed. Open and handle container with care. Do not eat, drink, or smoke while handling.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Avoid breathing fumes. Use only with adequate ventilation. Wear suitable protective clothing, gloves, and eye/face protection. Keep away from sources of ignition. Minimize dust generation and accumulation. Keep container tightly closed. Open and handle container with care. Do not eat, drink, or smoke while handling.
UN #'S Not Applicable
Packing Group Not Applicable
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