Angiogenesis is the process of building new vasculature and is inherently coordinated with building new tissue. Increased angiogenesis is a distinguishing characteristic of cancer growth, as it indicates a tumor is developing or has developed its own blood supply. AG Scientific supplies a variety of reagents that can identify or inhibit angiogenesis.  Our most popular are:

• Thalidomide is an angiogenesis inhibitor, it inhibits TNF-alpha biosynthesis.

• 17-AAGis an ansamycin antibiotic which binds with a high affinity into the ATP binding pocket in Hsp90 and induces the degradation of proteins.

• Fumagillin is an inhibitor of endothelial cell proliferation and is currently being investigated as potential treatment of intestinal microsporidiosis.

• Geldanamycin is a benzoquinone ansamycin antibiotic which binds to Hsp90 (Heat Shock Protein 90) and alters it function.

AG Scientific delivers quality assured reagents directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

  

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  1. (+/-)-Thalidomide
    (+/-)-Thalidomide
    T-1020

    Starting at $91.57

  2. (-)-Epigallocatechin gallate
    (-)-Epigallocatechin gallate
    E-2002

    Starting at $100.51

  3. (R,S)-Lenalidomide
    (R,S)-Lenalidomide
    L-2170

    Starting at $61.42

  4. 17-AAG (Tanespimycin) chemical structure | Hsp 90 Inhibitor | Anti-tumor | AG Scientific, Inc.
    17-AAG
    A-1256

    Starting at $41.54

  5. 17-DMAG
    17-DMAG
    A-1298

    Starting at $55.83

  6. 2-Phthalimidino-glutaric acid
    2-Phthalimidino-glutaric acid
    P-1187

    Starting at $46.89

  7. Anacardic Acid
    Anacardic Acid
    A-2186

    Starting at $77.06

  8. Bleomycin Sulfate
    Bleomycin Sulfate
    B-1269

    Starting at $185.00

  9. Borrelidin
    Borrelidin
    B-1260

    Starting at $351.46

  10. Calcitriol chemical structure | CAS 32222-06-3 | Vitamin D3 | AG Scientific, Inc.
    Calcitriol
    C-1026

    Starting at $189.99

  11. Ciprofloxican | CAS 85721-33-1 | Fluoroquinolone Antibacterial | AG Scientific, Inc.
    Ciprofloxacin
    C-2376

    Starting at $75.94

  12. COMP, Rat: Angiopoietin-1, Soluble, Human, Recombinant
    COMP, Rat: Angiopoietin-1, Soluble, Human, Recombinant
    A-1304

    Starting at $489.14

  13. Cytochalasin E
    Cytochalasin E
    C-1197

    Starting at $58.07

  14. DZNep,  Methyl transferase inhibitor
    DZNep, Methyl transferase inhibitor
    D-2639

    Starting at $148.60

  15. Fumagillin
    Fumagillin
    F-1028

    Starting at $50.86

  16. Geldanamycin | CAS 30562-34-6 | Binds HSP90 | Anti-Tumor Activity
    Geldanamycin
    G-1047

    Starting at $45.45

  17. GM6001
    GM6001
    G-1231

    Starting at $0.00

  18. Herbimycin A, Streptomyces Hygroscopicus
    Herbimycin A, Streptomyces Hygroscopicus
    H-1050

    Starting at $162.32

  19. Mithramycin A, Streptomyces plicatus
    Mithramycin A, Streptomyces plicatus
    M-1072

    Starting at $119.78

  20. N-Oxalyl-D-alanine
    N-Oxalyl-D-alanine
    O-1102

    Starting at $63.65

  21. NSC-23766
    NSC-23766
    N-1217

    Starting at $72.59

  22. Pomalidomide
    Pomalidomide
    P-3400

    Starting at $64.99

  23. SU 6656
    SU 6656
    S-2096

    Starting at $150.77

  24. SU6668
    SU6668
    S-2120

    Starting at $150.77

  25. Sulochrin, Aspergillus terreus
    Sulochrin, Aspergillus terreus
    S-2060

    Starting at $206.60

  26. Temsirolimus
    Temsirolimus
    T-2453

    Starting at $295.94

  27. Thiolutin
    Thiolutin
    T-1226

    Starting at $67.00

  28. Tie-2 Inhibitor 13
    Tie-2 Inhibitor 13
    T-1182

    Starting at $0.00

  29. Tranilast
    Tranilast
    T-1048

    Starting at $53.61

  30. Withaferin A, WFA
    Withaferin A, WFA
    W-1042

    Starting at $88.22

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