Cephalexin, Monohydrate

SKU
C-2749
  • CAS:23325-78-2
  • Formula:C16H17N3O4S • H2O
  • MW:365.4 Da
  • Appearance:White to off-white powder

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Product Name Qty
Cephalexin, Monohydrate
5 g
$66.29
Cephalexin, Monohydrate
10 g
$112.19

Description

Cephalexin is a first-generation antibiotic of the cephalosporin class which demonstrates antimicrobial effects against both Gram-positive and Gram-negative bacteria, albeit with generally greater efficacy against Gram-positive organisms. Cephalexin binds to penicillin binding proteins on bacterial cells walls, thus inhibiting peptidoglycan linking and weakening the cell wall.

Applications

Cephalexin is used in clinical medicine as a treatment for skin, ear, respiratory, urinary tract and bone infections. Recent research into cephalexin has focused on the potential uses of this and other cephalosporin antibiotics as radiosensitizers in cancer treatment. When administered in conjunction with radiation treatment, cephalosporins have been shown to slow tumor growth and increase the level of DNA damage achieved by ionizing radiation. Researchers believe that reactive oxygen species associated with cephalosporins may be responsible for this effect.

 

More Information
Alternate Name/Synonyms
Cephalexin hydrate, Ceporex, Ceporexin, Ibilex, Keforal, Keflex, Larixin, Oracef, Servispor
SKU
C-2749
CAS #
23325-78-2
Chemical Name
(6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
Chemical Formula
C16H17N3O4S • H2O
Molecular Weight
365.4 Da
Appearance
White to off-white powder
Solubility
Slightly soluble in water. Practically insoluble in alcohol, chloroform, and ether.
Storage Temp
2-8°C
THERAPEUTIC AREA
Not Available
USE
Cephalexin, Monohydrate is a pharmacopoeia reference standard.
Handling
Use in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Use in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.
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