Chrysomycin A

SKU
C-1410
  • CAS:82196-88-1
  • Formula:C28H28O9
  • MW:508.5
  • Appearance:Yellow Lyophilisate
  • Purity:99% by HPLC

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Starting at $243.48

Product Name Qty
Chrysomycin A, Streptomyces sp.
0.5 mg
$243.48
Chrysomycin A, Streptomyces sp.
2.5 mg
$860.27
Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives, isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomyin A has a potent antibacterial, antifungal, antiviral and antitumor profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated crosslinkers of DNA to histones.
More Information
Alternate Name/Synonyms
Chrysomycin V, Albacarcin V, Virenomycin V,
SKU
C-1410
CAS #
82196-88-1
Chemical Name
8-ETHENYL-1-HYDROXY-10,12-DIMETHOXY-4-[(2S,3S,4R,5S,6R)-3,4,5-TRIHYDROXY-4,6-DIMETHYLOXAN-2-YL]NAPHTHO[1,2-C]ISOCHROMEN-6-ONE
Chemical Formula
C28H28O9
Molecular Weight
508.5
Appearance
Yellow Lyophilisate
Purity
99% by HPLC
Solubility
Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol.
Stability
N/A
Storage Temp
+4°C
THERAPEUTIC AREA
Oncological Disorders
USE
Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives
MDL NUMBER
MFCD07370133
CHEMACX
X1495721-0
INCHI
InChI=1S/C28H28O9/c1-6-13-9-16-20(18(10-13)34-4)15-11-19(35-5)22-17(29)8-7-14(21(22)23(15)37-27(16)32)24-26(31)28(3,33)25(30)12(2)36-24/h6-12,24-26,29-31,33H,1H2,2-5H3/t12-,24+,25+,26+,28-/m1/s1
SMILES
C[C@@H]1[C@@H]([C@@]([C@H]([C@@H](O1)c2ccc(c3c2c4c(cc3OC)c5c(cc(cc5OC)C=C)c(=O)o4)O)O)(C)O)O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Promo text for AGS discount
N/A
UN #'S Not Applicable
Packing Group Not Applicable
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