Citalopram (hydrobromide); Bonitrile; Lu 10-171B; Nitalapram; Prepram
59729-32-7
405.3
C20H21FN2O • HBr
DMF, DMSO, Ethanol, PBS (pH 7.2)
-20°C
Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI) that targets the serotonin transporter within synaptic clefts. As a result, citalopram is capable of inhibiting serotonin uptake without exerting a significant inhibitory effect on dopamine or norepinephrine.
Citalopram is often prescribed in clinical medicine as an antidepressant. In addition, citalopram is known to have a wide range of off-label uses, including the treatment of generalized anxiety disorder and obsessive-compulsive disorder. It has also been shown to offer cardioprotective benefits by inhibiting platelet aggregation induced by collagen. Recent research has demonstrated that citalopram can induce epigenetic changes in the human genome by altering methylation of several hundred individual genes.
Displays cardioprotective effects in part by reducing expression of cytokine-induced endothelial adhesion molecules, ICAM-1 and VCAM-1. Attenuates ethanol intake.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
