Clindamycin hydrochloride

SKU
C-2653
  • CAS:21462-39-5
  • Formula:C18H34Cl2N2O5S
  • MW:461.4 Da
  • Appearance:White solid
  • Purity:>98% by HPLC
Product Name Qty
Clindamycin hydrochloride
5 g
$574.27
Clindamycin hydrochloride
5 mg
$91.07
Clindamycin hydrochloride
25 mg
$318.03

Description

Clindamycin hydrochloride is a salt of clindamycin, a semi-synthetic lincosamide. The hydrochloride salt forms at the basic N-ethylproline moiety and is the preferred pharmaceutical formulation.

Like other members of the lincosamide family, clindamycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin hydrochloride acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin hydrochloride has been extensively studied with over 8,000 literature citations.

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Clindamycin HCl; 7-Chloro-7-deoxylincomycin hydrochloride; 7-Chlorolincomycin hydrochloride
SKU
C-2653
CAS #
21462-39-5
Chemical Name
(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
Chemical Formula
C18H34Cl2N2O5S
Molecular Weight
461.4 Da
Appearance
White solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
Melting Point
141 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Broad spectrum antibiotic effective against anaerobic bacteria and protozoans.
MDL NUMBER
MFCD07793327
INCHI
InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
SMILES
CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl.Cl
Peptide sequence
Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Avoid breathing fumes. Use only with adequate ventilation. Wear suitable protective clothing, gloves, and eye/face protection. Keep away from sources of ignition. Minimize dust generation and accumulation. Keep container tightly closed. Open and handle container with care. Do not eat, drink, or smoke while handling.
GHS PICTOGRAMS
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