Cochlioquinone A

SKU
C-1401
  • CAS:32450-25-2
  • Formula:C30H44O8
  • MW:532.67
  • Appearance:Yellow Lyophilisate
  • Purity:99% by HPLC
Product Name Qty
Cochlioquinone A
2.5 mg
$1,036.34
Cochlioquinone A
0.5 mg
$295.94

Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Found to be an antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1).It is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADHubiquinone reductase. Newly isolated microbial agent. Demonstrates anti-angiogenic activity. Isolated from Bipolaris zeicola.

More Information
Alternate Name/Synonyms
Luteoleersin
SKU
C-1401
CAS #
32450-25-2
Chemical Name
(2S,3R,4S)-2-[(3R,4AR,6AR,12S,12AS,12BR)-12-HYDROXY-3-(2-HYDROXY-2-PROPANYL)-6A,12B-DIMETHYL-8,11-DIOXO-1,2,3,4A,5,6,6A,8,11,12,12A,12B-DODECAHYDROPYRANO[3,2-A]XANTHEN-9-YL]-4-METHYL-3-HEXANYL ACETATE
Chemical Formula
C30H44O8
Molecular Weight
532.67
Appearance
Yellow Lyophilisate
Purity
99% by HPLC
Solubility
Soluble in Methanol; DMSO Soluble in water (60°C, sonification) up to 6mg/ml
Stability
N/A
Storage Temp
+4°C
THERAPEUTIC AREA
Infectious Diseases
USE
Antiangiogenic and nematocidal activities. Antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1)
MDL NUMBER
MFCD08062299
CHEMACX
X2963587-2
INCHI
InChI=1S/C30H44O8/c1-9-15(2)25(36-17(4)31)16(3)18-14-19(32)22-24(34)27-29(7)12-10-20(28(5,6)35)37-21(29)11-13-30(27,8)38-26(22)23(18)33/h14-16,20-21,24-25,27,34-35H,9-13H2,1-8H3/t15-,16-,20+,21+,24+,25+,27+,29-,30+/m0/s1
SMILES
CC[C@H](C)[C@H]([C@@H](C)C1=CC(=O)C2=C(C1=O)O[C@@]3(CC[C@@H]4[C@@]([C@H]3[C@@H]2O)(CC[C@@H](O4)C(C)(C)O)C)C)OC(=O)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
E-Guides
N/A
Blog Post
N/A
Certificate of Analysis 1
Promo text for AGS discount
N/A
GHS PICTOGRAMS
UN #'S Not Applicable
Packing Group Not Applicable
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