Coelenterazine

SKU
C-1212
  • CAS:55779-48-1
  • Formula:C26H21N3O3
  • MW:423.5 Da
  • Appearance:Brown solid
  • Purity:≥95%

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Product Name Qty
Coelenterazine
50 ug
$107.64

Description:

Cell permeable, very sensitive and specific chemiluminescence probe of the superoxide anion and peroxynitrite. When oxidized by oxygen it illuminates blue light at 446nm when Ca2+ binds to the complex. Coelenterazine was originally isolated from Aequorea victoriaMany of the coelenterazine analogs possess properties different from those of native coelenterazine. These include half-life, aequorin regeneration rate, luminescence capacity, emission maximum and membrane permeability.

Applications:

• gene reporter assays
• whole animal assays
• biochemical assays
• live-cell assays for the detection of calciem ions

More Information
Alternate Name/Synonyms
2-[(4-Hydroxyphenyl)methyl]-6-(4-hydroxyphenyl)-8-(phenylmethyl)-imidazo [1,2-a] pyrazin-3-(7H)-one; Oplophorus luciferin; Coelenterazine native;
SKU
C-1212
CAS #
55779-48-1
Chemical Name
2-[(4-Hydroxyphenyl)methyl]-6-(4-hydroxyphenyl)-8-(phenylmethyl)-imidazo [1,2-a] pyrazin-3-(7H)-one
Chemical Formula
C26H21N3O3
Molecular Weight
423.5 Da
Appearance
Brown solid
Purity
≥95%
Solubility
Slightly soluble in methanol or ethanol. Avoid DMSO.
Stability
N/A
Melting Point
N/A
Preparation
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Coelenterazine is a cell-permeable aequorin luminophore that acts as a very sensitive and specific chemiluminescent probe for the superoxide anion
Merck Index
N/A
MDL NUMBER
MFCD00467176
CHEMACX
X1077031-5
INCHI
InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
SMILES
c1ccc(cc1)Cc2c-3nc(c(=O)n3cc([nH]2)c4ccc(cc4)O)Cc5ccc(cc5)O
Peptide sequence
N/A
RTECS
N/A
UN #'S
N/A
PACKING GROUP
N/A
HAZARD CLASS
N/A
Handling
Protect from Light
Certificate of Analysis 1
Certificate of Analysis 2
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from Light
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