Curcumin, Curcuma longa (High Purity)

SKU
C-2275
  • CAS:458-37-7
  • Formula:C21H20O6
  • MW:368.38
  • Appearance:Orange-yellow Solid
  • Purity:98%

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Product Name Qty
Curcumin, Curcuma longa (High Purity)
10 mg
$53.61
Curcumin, Curcuma longa (High Purity)
50 mg
$184.26

Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC= 8 M)and cyclooxygenase (COX) (IC= 52 M). Also inhibits glutathione S-transferase,induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an ICof ~25 M. Does not affect p300/CREB binding protein-associated factor (PCAF).

More Information
Alternate Name/Synonyms
1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
SKU
C-2275
CAS #
458-37-7
Chemical Name
1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
Chemical Formula
C21H20O6
Molecular Weight
368.38
Appearance
Orange-yellow Solid
Purity
98%
Solubility
DMSO (25 mg/ml) or EtOH (10 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Curcumin (Synthetic), a phenolic pigment originally isolated from Curcuma longa (tumeric) has reported antioxident, anticancer and anti-inflammatory actvities
MDL NUMBER
MFCD00008365
CHEMACX
X1001092-3
INCHI
InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
SMILES
COc1c(ccc(c1)/C=C/C(=O)CC(=O)/C=C/c2cc(c(cc2)O)OC)O
RTECS
MI5230000
Handling
Protect from air and light
GHS PICTOGRAMS
Handling Protect from air and light
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