Cycloheximide N-ethyl ethanoate

SKU
C-2597
  • Formula:C19H29NO6
  • MW:367.4 Da
  • Appearance:White powder
  • Purity:≥99%

0

0

0

Product Name Qty
Cycloheximide N-ethyl ethanoate
10 mg
$113.90

FKBP12 inhibitor

More Information
SKU
C-2597
Chemical Name
ethyl 2-[4-[(2R)-2-[(3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-dioxopiperidin-1-yl]acetate
Chemical Formula
C19H29NO6
Molecular Weight
367.4 Da
Appearance
White powder
Purity
≥99%
Solubility
May be dissolved in DMSO(15 mg/ml) or Ethanol (3 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Not Applicable
USE
FKBP12 inhibitor (IC50=4.4 µM) with neuroregenerative properties. Does not inhibit protein synthesis (as does cycloheximide). Mimics a helical peptide in target proteins for binding to the immunophillin Mip homolog, BpML1 (Burkholderia pseudomallei Mip-like protein 1).
INCHI
InChI=1S/C19H29NO6/c1-4-26-18(24)10-20-16(22)8-13(9-17(20)23)7-15(21)14-6-11(2)5-12(3)19(14)25/h11-15,21H,4-10H2,1-3H3/t11-,12-,14?,15+/m0/s1
SMILES
CCOC(=O)CN1C(=O)CC(CC1=O)C[C@H](C2C[C@H](C[C@@H](C2=O)C)C)O
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
Handling Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
To Top