Cycloheximide Solution (100 mM)

SKU
C-2276
  • CAS:66-81-9
  • Formula:C15H23NO4
  • MW:281.35
  • Appearance:Liquid
  • Purity:95%

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Product Name Qty
Cycloheximide Solution (100 mM)
1 ml
$79.75

A very active antibiotic against many yeasts and fungi. Inhibits protein synthesis in eukaryotes (but not in prokaryotes) by interfering with the translocation step. It inhibits chain initiation as well as chain elongation by acting on the 60S subunit of the eukaryote ribosome, interacting directly with enzyme translocase. Cycloheximide is used as an inhibitor to study cell-free protein biosynthesis in eukaryotes and also used to block ribosome-dependent in vivo polypeptide synthesis. It induces apoptosis in a variety of cells, but can also delay or inhibit apoptosis by other agents.

More Information
Alternate Name/Synonyms
CHX, 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A
SKU
C-2276
CAS #
66-81-9
Chemical Name
3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A
Chemical Formula
C15H23NO4
Molecular Weight
281.35
Appearance
Liquid
Purity
95%
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Cycloheximide is a highly effective antibiotic with activity against mold, yeast, and phytopathogenic fungi, with lower activity against bacteria
MDL NUMBER
MFCD00082346
CHEMACX
X1006248-5
INCHI
InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
SMILES
C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C
Peptide sequence
Not Applicable
RTECS
MA4375000
UN #'S
UN 2811
PACKING GROUP
I
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Certificate of Analysis 1
Certificate of Analysis 2
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S UN 2811
Packing Group I
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