Cyclopamine

SKU
C-1405
  • CAS:4449-51-8
  • Formula:C27H41NO2
  • MW:411.6
  • Appearance:White Solid
  • Purity:98%

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Product Name Qty
Cyclopamine
1 mg
$43.29
Cyclopamine
5 mg
$97.39
Cyclopamine is a steroidal alkaloid that blocks sonic hedgehog signaling. It demonstrates teratogenic properties, as well as, promising anti-tumor properties.
More Information
Alternate Name/Synonyms
11-Deoxyjervine
SKU
C-1405
CAS #
4449-51-8
Chemical Name
(2'R,3S,3'R,3A'S,6AR,6BS,6'S,7A'R,11AS,11BR)-3',6',10,11B-TETRAMETHYL-1,2,3,3A',4,4',5',6,6A,6B,6',7,7',7A',8,11,11A,11B-OCTADECAHYDRO-3'H-SPIRO[BENZO[A]FLUORENE-9,2'-FURO[3,2-B]PYRIDIN]-3-OL
Chemical Formula
C27H41NO2
Molecular Weight
411.6
Appearance
White Solid
Purity
98%
Solubility
Soluble in DMSO, DMF, Ethanol.
Stability
N/A
Melting Point
227-230°C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A hedgehog [Hh] signaling pathway and Smo inhibitor
MDL NUMBER
MFCD09878269
CHEMACX
X1012243-7
INCHI
InChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17,19-21,23-25,28-29H,6-14H2,1-4H3/t15-,17+,19-,20-,21-,23-,24+,25-,26-,27-/m0/s1
SMILES
C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1
Peptide sequence
Not Applicable
RTECS
GY0750000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Warning.Toxic. May be Teratogenic. Wear gloves/ mask when handling product. Avoid contact by all means of exposure.
Certificate of Analysis 1
Certificate of Analysis 2
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Warning.Toxic. May be Teratogenic. Wear gloves/ mask when handling product. Avoid contact by all means of exposure.
UN #'S Not Applicable
Packing Group Not Applicable
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