Cyclopiazonic Acid

SKU
C-1025
  • CAS:18172-33-3
  • Formula:C20H20N2O3
  • MW:336.4
  • Appearance:Off-white crystals
  • Purity:≥98% by HPLC

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Product Name Qty
Cyclopiazonic Acid
10 mg
$142.80
Cyclopiazonic acid, Penicillium cyclopium
50 mg
$561.00

Description

Cyclopiazonic acid is a reversible inhibitor of endoplasmic reticulum Ca2+ ATPase. Does not increase IP3 levels. Specific inhibitor of Ca2+- ATPase of sarcoplasmic reticulum, inhibiting the enzyme completely at 6-8 nmol/mg protein (at 0.5-2.0M ATP).

Isolated from Penicillium cyclopium.

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
SKU
C-1025
CAS #
18172-33-3
Chemical Name
(6AR,11AS,11BR)-REL-10-ACETYL-2,6,6A,7,11A,11B-HEXAHYDRO-7,7-DIMETHYL-9H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-9-ONE
Chemical Formula
C20H20N2O3
Molecular Weight
336.4
Appearance
Off-white crystals
Purity
≥98% by HPLC
Solubility
DMSO, Methylene Chloride and Methanol.
Melting Point
240°C
Storage Temp
-20°C
USE
Cyclopiazonic acid (CPA) is a toxic fungal secondary metabolite
MDL NUMBER
MFCD00167445
CHEMACX
X1009681-2
INCHI
InChI=1S/C20H20N2O3/c1-9(23)14-18(24)17-16-11-8-21-13-6-4-5-10(15(11)13)7-12(16)20(2,3)22(17)19(14)25/h4-6,8,12,16-17,21,23H,7H2,1-3H3/b14-9-/t12-,16+,17+/m1/s1
SMILES
C/C(=C/1C(=O)[C@@H]2[C@@H]3[C@@H](CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)/O
Peptide sequence
Not Applicable
RTECS
UY8587000
UN #'S
UN 2811
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
UN #'S UN 2811
Packing Group II
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