Cyclopiazonic acid is a reversible inhibitor of endoplasmic reticulum Ca2+ ATPase. Does not increase IP3 levels. Specific inhibitor of Ca2+- ATPase of sarcoplasmic reticulum, inhibiting the enzyme completely at 6-8 nmol/mg protein (at 0.5-2.0M ATP).
Isolated from Penicillium cyclopium.
Not for human therapeutic use or for medicinal purposes. For research applications only.
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|UN #'S||UN 2811|