Cyclopiazonic acid, Penicillium cyclopium

SKU
C-1025
  • CAS:18172-33-3
  • Formula:C20H20N2O3
  • MW:336.4
  • Appearance:Off-White Crystals
  • Purity:97%

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Product Name Qty
Cyclopiazonic acid, Penicillium cyclopium
10 mg
$128.43
Cyclopiazonic acid, Penicillium cyclopium
50 mg
$513.70

Reversible inhibitor of endoplasmic reticulum Ca2+ ATPase. Does not increase IP3 levels. Specific inhibitor of Ca2+- ATPase of sarcoplasmic reticulum, inhibiting the enzyme completely at 6-8 nmol/mg protein (at 0.5-2.0M ATP).

More Information
SKU
C-1025
CAS #
18172-33-3
Chemical Name
(6AR,11AS,11BR)-REL-10-ACETYL-2,6,6A,7,11A,11B-HEXAHYDRO-7,7-DIMETHYL-9H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-9-ONE
Chemical Formula
C20H20N2O3
Molecular Weight
336.4
Appearance
Off-White Crystals
Purity
97%
Solubility
Soluble in Methylene Chloride and Methanol
Melting Point
243-245°C
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Cyclopiazonic acid (CPA) is a toxic fungal secondary metabolite
MDL NUMBER
MFCD00167445
CHEMACX
X1009681-2
INCHI
InChI=1S/C20H20N2O3/c1-9(23)14-18(24)17-16-11-8-21-13-6-4-5-10(15(11)13)7-12(16)20(2,3)22(17)19(14)25/h4-6,8,12,16-17,21,23H,7H2,1-3H3/b14-9-/t12-,16+,17+/m1/s1
SMILES
C/C(=C/1C(=O)[C@@H]2[C@@H]3[C@@H](CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)/O
Peptide sequence
Not Applicable
RTECS
UY8587000
UN #'S
UN 2811
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Warning.Potent Neurotoxin. Wear gloves/ mask when handling product. Avoid contact by all means of exposure.
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Warning.Potent Neurotoxin. Wear gloves/ mask when handling product. Avoid contact by all means of exposure.
UN #'S UN 2811
Packing Group II
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