Cyclosporin A

SKU

C-1199

CAS:59865-13-3
Formula:C₆₂H₁₁₁N₁₁O₁₂
MW:1202.6 Da
Appearance:White powder
Purity:>98% (HPLC)

SDS

CofA

Product Name	Qty
Cyclosporin A, Fusarium solani 1 g $300.00
Cyclosporin A, Fusarium solani 500 mg $199.99
Cyclosporin A, Fusarium solani 100 mg $54.99

Details

Potent immunosuppressor. Inhibitor of the mitochondrial permeability transition pore (MPTP), preventing necrosis in several models. Isolated from Fusarium solani. Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells. The Influence of B-Cell Lymphoma 2 Protein, an Antiapoptotic Regulator of Mitochondrial Permeability Transition, on Isoflurane-Induced and Ischemic Postconditioning in Rabbits.Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells.

Reviews

Safety

GHS PICTOGRAMS
Handling	Warning. Toxic. Wear gloves/mask when handling product. Avoid contact by all means of exposure.

Citations

Citations	Regulator of Calcineurin 1 Isoform 4 (RCAN1.4) Is Overexpressed in the Glomeruli of Diabetic Mice
	Cellular accumulation of dietary anticarcinogenic isothiocyanates is followed by transporter-mediated export as dithiocarbamates
	Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells
	The influence of B-cell lymphoma 2 protein, an antiapoptotic regulator of mitochondrial permeability transition, on isoflurane-induced and ischemic postconditioning in rabbits
	Synapsin regulates vesicle organization and activity-dependent recycling at Drosophila motor boutons
	Synapsin maintains the reserve vesicle pool and spatial segregation of the recycling pool in Drosophila presynaptic boutons
	Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R
	Calcineurin serves in the circadian output pathway to regulate the daily rhythm of L-type voltage-gated calcium channels in the retina

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