5-(N-methyl-D-valine)-Cyclosporin A; Sandoz 37-839
83602-39-5
1202.6
C62H111N11O12
Slightly soluble in Chloroform and Methanol
-20°C
Cyclosporin H is a minor analogue of the cyclosporin family which is immunologically inactive as it does not bind to immunophilin. Cyclosporin H is the most extensively investigated of the minor cyclosporin analogues .
It is a potent inhibitor of tumor-promoting phorbol esters on mouse skin in vivo, and of calcium/calmodulin-dependent EF-2 phosphorylation in vitro, a potent and selective antagonist of formyl peptide receptor and inhibitor of formyl peptide-induced superoxide formation.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
