D-NMMA (Acetate)

SKU

D-1027

CAS:137694-75-8
Formula:C₇H₁₆N₄O₂•C₂H₄O₂
MW:248.283 Da
Appearance:White Crystalline Solid
Purity:≥98%

SDS

CofA

Product Name	Qty
D-NMMA·Monoactetate 25 mg $113.90
D-NMMA·Monoactetate 100 mg $341.72

Details

Description

D-NMMA is inactive as an inhibitor of NOS and may be used to explore non-specific effects of L-NMMA. Negative control for L-NMMA.

Not for human therapeutic use or for medicinal purposes. For research applications only.

Specifications

More Information

Alternate Name/Synonyms

D-NMMA; D-Tilarginine; D-Targinine

SKU

D-1027

CAS #

137694-75-8

Chemical Name

acetic acid;(2R)-2-amino-5-[(N'-methylcarbamimidoyl)amino]pentanoic acid

Chemical Formula

C₇H₁₆N₄O₂•C₂H₄O₂

Molecular Weight

248.283 Da

Appearance

White Crystalline Solid

Purity

≥98%

Solubility

Soluble in water or methanol

Storage Temp

-20°C, desiccated

THERAPEUTIC AREA

Not Applicable

USE

D-NG-Monomethylarginine (D-NMMA) is a cell permeable, negative control for NG-Monomethyl-L-arginine, L-NMMA (sc-200739). D-NMMA may be employed to investigate non-specific L-NMMA activity. D-NMMA does not have any significant effect on NOS.

Handling

Handle in accordance with good industrial hygiene and safety practice.

Citations

PATHOGENESIS AND IMMUNITY: Myeloid-Derived Suppressor Cells in Murine Retrovirus-Induced AIDS Inhibit T- and B-Cell Responses In Vitro That Are Used To Define the Immunodeficiency Kathy A. Green, W. James Cook, and William R. Green J. Virol., Feb 2013; 87: 2058 - 2071.

Citations_Hyperlink

http://jvi.asm.org/cgi/content/abstract/87/4/2058?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&andorexacttitle=and&andorexacttitleabs=and&fulltext=A.G.+Scientific&andorexactfulltext=phrase&searchid=1&FIRSTINDEX=0&fdate=1/1/2000&resourcetype=HWCIT

Certificate of Analysis 1

D-1027, K1012A.pdf

Certificate of Analysis 2

D-1027, H1050.pdf

Certificate of Analysis 3

D-1027, E1156.pdf

Reviews

Safety

Handling	Handle in accordance with good industrial hygiene and safety practice.

Citations

Citations	Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin
	Role of nitric oxide in pathogenesis of herpes simplex virus encephalitis in rats
	Myeloid-derived suppressor cells in murine retrovirus-induced AIDS inhibit T- and B-cell responses in vitro that are used to define the immunodeficiency