D4476

SKU
C-2279
  • CAS:301836-43-1
  • Formula:C23H18N4O3
  • MW:398.41
  • Appearance:Off-White Solid
  • Purity:98% by HPLC

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Product Name Qty
D4476
1 mg
$85.43
D4476
5 mg
$336.03
A cell-permeable, ATP-competitive inhibitor of casein kinase 1 (CK1) (IC= 0.3 M). Also inhibits ALK5 (IC= 0.5 M) and p38MAP kinase (IC= 12 M). Displays selectivity over many other protein kinases.
More Information
Alternate Name/Synonyms
4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl) -1H-imidazol-2-yl]benzamide
SKU
C-2279
CAS #
301836-43-1
Chemical Name
4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl) -1H-imidazol-2-yl]benzamide
Chemical Formula
C23H18N4O3
Molecular Weight
398.41
Appearance
Off-White Solid
Purity
98% by HPLC
Solubility
DMSO (100 mM)
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
A cell-permeable, ATP-competitive inhibitor of casein kinase 1
MDL NUMBER
MFCD09037526
CHEMACX
X1621492-1
INCHI
InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27)
SMILES
c1ccnc(c1)c2c(nc([nH]2)c3ccc(cc3)C(=O)N)c4ccc5c(c4)OCCO5
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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