- MW:432.5 Da
- Appearance:White to off-white solid
DAPT is a cell permeable inhibitor of γ-secretase (IC=115 nM for totalamyloid, IC=200 nM foramyloid 1-42). It does not inhibit presenilinase. DAPT antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stel cell-derived embryoid bodies independent of sonic hedgehog (Shh) signaling.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Packaged under inert gas. Protect from light.|