Davercin

SKU
D-2467
  • CAS:55224-05-0
  • Formula:C38H65NO14
  • MW:759.9
  • Appearance:White solid
  • Purity:>98% by HPLC
Product Name Qty
Davercin
1 mg
$176.55
Davercin
5 mg
$617.38
*Please inquire the availability for this product. Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple modification improves the stability and hydrophobicity of the macrocyclic structure. Davercin shows comparable or better in vitro potency, low host toxicity and improved pharmacokinetics compared with erythromycin.
More Information
Alternate Name/Synonyms
Erythromycin A 11,12-carbonate, Erythromycin A cyclic 11,12-carbonate, Erythromycin cyclic carbonate
SKU
D-2467
CAS #
55224-05-0
Chemical Formula
C38H65NO14
Molecular Weight
759.9
Appearance
White solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF, DMSO Limited water solubility
Storage Temp
-20°C
MDL NUMBER
MFCD01729176
INCHI
InChI=1S/C38H65NO14/c1-14-25-38(10)32(52-35(44)53-38)20(4)27(40)18(2)16-36(8,45)31(51-34-28(41)24(39(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-37(9,46-13)30(42)23(7)48-26/h18-26,28-32,34,41-42,45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30+,31?,32-,34+,36-,37-,38-/m1/s1
SMILES
CC[C@@H]1[C@@]2([C@@H]([C@H](C(=O)[C@@H](C[C@@](C([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)C)OC(=O)O2)C
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