Deforolimus

SKU
C-2285
  • CAS:572924-54-0
  • Formula:C53H84NO14P
  • MW:989.56
  • Appearance:White to off-white Solid
  • Purity:99% by HPLC
Product Name Qty
Deforolimus
5 mg
$329.44
Deforolimus
25 mg
$999.48
A small-molecule inhibitor of the mammalian target of rapamycin (mTOR). Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.
More Information
Alternate Name/Synonyms
AP 23573, MK-8669, Ridaforolimus
SKU
C-2285
CAS #
572924-54-0
Chemical Name
(1R,2R,4S)-4-((2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1,18-DIHYDROXY-19,30-DIMETHOXY-15,17,21,23,29,35-HEXAMETHYL-2,3,10,14,20-PENTAOXO-11,36-DIOXA-4-AZATRICYCLO[30.3.1.04,9] HEXATRIACONTA-16,24,26,28-TETRAEN-12-YL]PROPYL)-2-METHOX
Chemical Formula
C53H84NO14P
Molecular Weight
989.56
Appearance
White to off-white Solid
Purity
99% by HPLC
Solubility
DMSO
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A selective FRAP (mTOR) inhibitor use in cancer
MDL NUMBER
MFCD13184816
CHEMACX
X1722909-7
INCHI
InChI=1S/C53H84NO14P/c1-32-18-14-13-15-19-33(2)44(63-8)30-40-23-21-38(7)53(61,67-40)50(58)51(59)54-25-17-16-20-41(54)52(60)66-45(35(4)28-39-22-24-43(46(29-39)64-9)68-69(11,12)62)31-42(55)34(3)27-37(6)48(57)49(65-10)47(56)36(5)26-32/h13-15,18-19,27,32,34-36,38-41,43-46,48-49,57,61H,16-17,20-26,28-31H2,1-12H3/b15-13+,18-14+,33-19+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
SMILES
C[C@@H]1CCC2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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