Description

Δ²-Ivermectin B1a is an irreversible base degradation product of ivermectin found in animals treated with ivermectin and in the environment. Δ²-Ivermectin B1a is formed by rearrangement of the naturally occurring Δ³-group to the 2-position. Despite the importance of ivermectin as an anthelmintic in animal health, there are no published reports of the biological activity or the levels of Δ²-Ivermectin B1a in animals or in the environment.

References

• Base-catalyzed isomerization of avermectins

• Determination of avermectins in plasma at nanogram levels using high-performance liquid chromatography with fluorescence detection

Not for human therapeutic use or for medicinal purposes. For research applications only.