Demeclocycline

SKU
D-2483
  • CAS:127-33-3
  • Formula:C21H21ClN2O8
  • MW:468.9
  • Appearance:Yellow to orange solid
  • Purity:>98% by HPLC
Product Name Qty
Demeclocycline
5 mg
$148.07
Demeclocycline
25 mg
$517.14
*Please inquire the availability for this product. Demeclocycline, a chlortetracycline analogue produced by a mutagenised strain of Streptomyces aureofaciens, was first isolated in 1957. Like all tetracyclines, demeclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Demeclocycline has been extensively cited in the literature with over 800 references relating almost exclusively to in vivo use.
More Information
Alternate Name/Synonyms
6-Demethylchlotetracycline, DMCT, 7-Chloro-6-demethyltetracycline, Ledermycin, RP 10192
SKU
D-2483
CAS #
127-33-3
Chemical Formula
C21H21ClN2O8
Molecular Weight
468.9
Appearance
Yellow to orange solid
Purity
>98% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Demeclocycline shows broad spectrum antibacterial and antiprotozoan activity 
MDL NUMBER
MFCD00864922
INCHI
InChI=1S/C21H21ClN2O8/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31)/t6-,7-,14-,15-,21-/m0/s1
SMILES
CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O)Cl)O
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