Demeclocycline hydrochloride

SKU
D-2485
  • CAS:64-73-3
  • Formula:C21H22Cl2N2O8
  • MW:501.3
  • Appearance:Yellow to orange solid
  • Purity:>98% by HPLC
Product Name Qty
Demeclocycline hydrochloride
25 mg
$387.28
Demeclocycline hydrochloride
5 mg
$110.48
*Please inquire the availability for this product. Demeclocycline hydrochloride is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, demeclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.
More Information
Alternate Name/Synonyms
6-Demethylchlotetracycline hydrochloride, 7-Chloro-6-demethyltetracycline hydrochloride, Declomycin, Ledermycin hydrocloride, RP 10192
SKU
D-2485
CAS #
64-73-3
Chemical Formula
C21H22Cl2N2O8
Molecular Weight
501.3
Appearance
Yellow to orange solid
Purity
>98% by HPLC
Solubility
Soluble in water (20 mg/ml), DMSO, and methanol
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Use for the treatment of infections caused by tetracycline-sensitive organisms
MDL NUMBER
MFCD00082371
INCHI
InChI=1S/C21H21ClN2O8.ClH/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31);1H/t6-,7-,14-,15-,21-;/m0./s1
SMILES
CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O)Cl)O.Cl
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