PF-00520904; PNU 141962; 2-deoxy-Paraherquamide
187865-22-1
479.6
C28H37N3O4
DMF, DMSO, Ethanol, Methanol
-20°C
Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel is a potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin.
Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
