Diaphorase (NADPH)

SKU

N-1185

CAS:9001-18-7
MW:48 kDa (gel filtration)
Appearance:Yellow lyophilized powder

SDS

CofA

Product Name	Qty
Diaphorase NADPH 1 KU $380.79

Details

Description

Diaphorase (NADPH) a nitric oxide synthase, is an oxidative enzyme present in a discrete population of interneurons. It has demonstrated selectivity labeling number of discrete populations of neurons throughout the nervous system. This technique has been used In many neuropathological studies and experiments.

Diaphorase NADPH histochemistry provides a specific histochemical marker for neurons producing nitric oxide. This method has been used to examine neurons in Huntington disease, Alzheimer disease, progressive supranuclear palsy, and ischemia. The source of Diaphorase NADPH is Bacillus megaterium bacteria.

Specifications

• EC 1.6.99.1
• Activity: 5/mg
• Contaminants: Myokinase ≤ 0.50%
• Optimal pH: 7.0-9.0
• Thermal Stability: stable at 60 C and below (pH 7.5, 10 min)

Specifications

More Information

Alternate Name/Synonyms

Old Yellow Enzyme; OYE; NADPH dehydrogenase; NADPH diaphorase; Diaphorase, NADPH2 dehydrogenase; Reduced nicotinamide adenine dinucleotide phosphate dehydrogenase

SKU

N-1185

CAS #

9001-18-7

Chemical Formula

N/A

Molecular Weight

48 kDa (gel filtration)

Appearance

Yellow lyophilized powder

Purity

N/A

Solubility

N/A

Melting Point

N/A

Preparation

N/A

Storage Temp

-20°C, desiccated

THERAPEUTIC AREA

Not Available

USE

Diaphorase (NADPH) has been used in a study to assess the protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. It has been used along with aldehyde dehydrogenase to construct a biosensor for acetaldehyde by immobilization.[ It has also been used in the reoxidation of NADP to NADPH.

Merck Index

N/A

RTECS

Not Applicable

UN #'S

Not Applicable

PACKING GROUP

Not Applicable

HAZARD CLASS

Not Applicable

Handling

Provide appropriate exhaust ventilation at places where dust is formed.