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Dimethylenastron

SKU
D-1300
  • CAS:863774-58-7
  • Formula:C16H18N2O2S
  • MW:302.4
  • Appearance:Yellow Solid
  • Purity:95%
Product Name Qty
Dimethylenastron
1 mg
$98.28
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Potent, cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC=200 nM) by binding to the mitotic kinesin Eg5.
More Information
Alternate Name/Synonyms
7,7-Dimethyl-4-(3-hydroxyphenyl)-5-oxo-3,4,5,6,7,8-hexahydroquinazolin-2(1H)-thione
SKU
D-1300
CAS #
863774-58-7
Chemical Name
7,7-Dimethyl-4-(3-hydroxyphenyl)-5-oxo-3,4,5,6,7,8-hexahydroquinazolin-2(1H)-thione
Chemical Formula
C16H18N2O2S
Molecular Weight
302.4
Appearance
Yellow Solid
Purity
95%
Solubility
Soluble in DMSO (10mg/ml) or methanol (5mg/ml).
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in inhibition of mitotic kinesin Eg5
MDL NUMBER
MFCD09264157
CHEMACX
X4983319-2
PubChecm ID
N/A
INCHI
InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)
SMILES
CC1(CC2=C(C(NC(=S)N2)C3=CC(=CC=C3)O)C(=O)C1)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial Protect from Light Caution: Harmful.
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Citations
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Structure Available (Y/N)
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Handling Store in Tightly Sealed Vial Protect from Light Caution: Harmful.
UN #'S Not Applicable
Packing Group Not Applicable
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