Dipeptidylpeptidase IV Inhibitor, K579

SKU
D-1306
  • CAS:440100-64-1
  • Formula:C17 H24 N6 O
  • MW:328.42 Da
  • Appearance:Off-white to light brown powder
  • Purity:≥98%

0

1

0

Starting at $102.80

Product Name Qty
Dipeptidylpeptidase IV Inhibitor
1 mg
$102.80
Dipeptidylpeptidase IV Inhibitor, K579
10 mg
$206.60
Dipeptidylpeptidase IV Inhibitor, K579
50 mg
$871.06
Dipeptidylpeptidase IV Inhibitor
5 mg
$167.73
Dipeptidyl peptidase IV inhibitor. Inhibits rat, canine, human and monkey enzymes with ICvalues of 3, 5, 8, and 8 nM respectively. Long-acting hypoglycemic agent. Beneficial as protein preservation stabilization inhibitor.
More Information
Alternate Name/Synonyms
DPP IV Inhibitor; dipeptidyl aminopeptidase IV inhibitor; CD26 inhibitor; glycoprotein GP110 inhibitor; glycylproline aminopeptidase inhibitor; Tp103 inhibitor; X-PDAP inhibitor; THAM inhibitor
SKU
D-1306
CAS #
440100-64-1
Chemical Name
(2S)-1-[2-[(4-methyl-1-pyrimidin-2-ylpiperidin-4-yl)amino]acetyl]pyrrolidine-2-carbonitrile
Chemical Formula
C17 H24 N6 O
Molecular Weight
328.42 Da
Appearance
Off-white to light brown powder
Purity
≥98%
Solubility
30 mg/ml in DMSO.
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Endocrinological Disorders
USE
Dipeptidylpeptidase IV Inhibitor IV, K579 is an agent that acts as a low-binding CD26 (dipeptidyl peptidase IV) inhibitor. The inhibitor is a cyanopyrrolidine compound that is more potent and acts as a slower binding inhibitor than the used dipeptidyl peptidase IV inhibitor, NVP-DPP728. Research shows that it can conserve endogenously secreted active forms of glucagon-lke peptide-1, heighten insulin response and can ameliorate glucose excursion.
MDL NUMBER
MFCD07364044
CHEMACX
X1763913-7
INCHI
InChI=1S/C17H24N6O/c1-17(21-13-15(24)23-9-2-4-14(23)12-18)5-10-22(11-6-17)16-19-7-3-8-20-16/h3,7-8,14,21H,2,4-6,9-11,13H2,1H3/t14-/m0/s1
SMILES
CC1(CCN(CC1)C2=NC=CC=N2)NCC(=O)N3CCC[C@H]3C#N
Handling
Handle in accordance with good industrial hygiene and safety practice.
Certificate of Analysis 1
Handling Handle in accordance with good industrial hygiene and safety practice.
To Top