Dirithromycin

SKU
D-2525
  • CAS:62013-04-1
  • Formula:C42H78N2O14
  • MW:835.1
  • Appearance:White solid
  • Purity:>98% by HPLC
Product Name Qty
Dirithromycin
5 mg
$110.48
Dirithromycin
25 mg
$387.28
*Please inquire the availability for this product. Dirithromycin is a macrolide antibiotic pro-drug of 9S-erythromycylamine, a close analogue of erythromycin in which the 9-keto group is replaced with an amino group in the S-configuration. Although erythromycylamine overcomes the acid instability of erythromycin, it is poorly absorbed following oral administration. Dirithromycin is formed by reacting erythromycylamine with an aldehyde to form a Schiff base which undergoes cyclisation to an oxazine with the C11-alcohol. Dirithromycin provides higher tissue levels and prolonged in vivo half-life by slowly releasing erythromycylamine.
More Information
Alternate Name/Synonyms
LY-237216
SKU
D-2525
CAS #
62013-04-1
Chemical Formula
C42H78N2O14
Molecular Weight
835.1
Appearance
White solid
Purity
>98% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Dirithromycin is a macrolide glycopeptide antibiotic. It is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis
MDL NUMBER
MFCD00865041
INCHI
InChI=1S/C42H78N2O14/c1-15-29-42(10,49)37-24(4)32(43-30(56-37)21-52-17-16-50-13)22(2)19-40(8,48)36(58-39-33(45)28(44(11)12)18-23(3)53-39)25(5)34(26(6)38(47)55-29)57-31-20-41(9,51-14)35(46)27(7)54-31/h22-37,39,43,45-46,48-49H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,30-,31+,32+,33-,34+,35+,36-,37-,39+,40-,41-,42-/m1/s1
SMILES
CC[C@@H]1[C@@]([C@H]2[C@H]([C@H]([C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)N[C@H](O2)COCCOC)C)(C)O
GHS PICTOGRAMS
To Top