Dimethyloxallyl Glycine
89464-63-1
175.1
C6H9NO5
DMF, DMSO, Ethanol, PBS (pH 7.2)
-20°C
DMOG [Dimethyloxallyl Glycine] inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1α and inhibiting JMJD2A (IC50 = 2.5 μM). Displays neuroprotective effects. Inhibits neuronal cell death caused by neurotrophin deprivation. DMOG prevents activation of the ATR/CHK1/p53 pathway and suppresses apoptosis induced by DNA damage.
Inhibits prolyl hydroxylase domain-containing proteins.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.