Doxycycline

SKU
D-2543
  • CAS:564-25-0
  • Formula:C22H24N2O8
  • MW:444.4 Da
  • Appearance:Yellow to orange solid
  • Purity:>98% by HPLC
Product Name Qty
Doxycycline
inquire - 5 mg
$0.00
Doxycycline
inquire - 25 mg
$0.00

Description

Doxycycline is a second-generation tetracycline molecule and a derivative of oxytetracycline. Used as a broad spectrum antibiotic, doxycycline exerts an antimicrobial effect by inhibiting the binding of tRNA to the 30S ribosomal subunit in prokaryotic cells. As a result of this blocking of the 30S subunit, doxycycline impedes protein synthesis and prevents cell replication.

Applications

Doxycycline is used in clinical medicine to treat a wide variety of bacterial infections. Conditions that may indicate for the administration of doxycycline include respiratory tract infections, typhus fever, cholera, urinary tract infections, E. coli infections and Rocky Mountain spotted fever. Recent research into doxycycline has focused on its effects on metabolism and gene expression, as well as its potential capacity to mediate inflammatory responses.

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
6- Deoxy-5-hydroxytetracycline, 6-Deoxyoxytetracycline, Doxytetracycline, GS 3065, Hydramycin, Vibramycin, Vibra-tabs
SKU
D-2543
CAS #
564-25-0
Chemical Name
(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
Chemical Formula
C22H24N2O8
Molecular Weight
444.4 Da
Appearance
Yellow to orange solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Melting Point
201 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
For laboratory and research purpose only.
MDL NUMBER
MFCD00800994
INCHI
InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1
SMILES
C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=C(C(=O)[C@]3(C(=C2C(=O)C4=C1C=CC=C4O)O)O)C(=O)N)O)N(C)C)O
Handling
Avoid physical contact with skins, eyes and clothing. Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
GHS PICTOGRAMS
HandlingAvoid physical contact with skins, eyes and clothing. Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
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