DPP IV Inhibitor, NVP DPP 728

SKU
D-2295
  • CAS:247016-69-9
  • Formula:C15H18N6O.2HCl
  • MW:371.27
  • Appearance:White Solid
  • Purity:98% by HPLC

Starting at $94.92

Product Name Qty
DPP IV Inhibitor, NVP DPP 728
1 mg
$94.92
DPP IV Inhibitor, NVP DPP 728
5 mg
$379.69
A potent, selective, reversible, and slow binding dipeptidyl peptidase IV inhibitor (IC= 14 nM). Displays 15,000 fold selectivity over DPP-II and a range of Proline-cleaving proteases. Displays anti-diabetic activity in vivo, improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, and augments insulin secretion and GLUT-2 levels.
More Information
Alternate Name/Synonyms
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile Dihydrochloride
SKU
D-2295
CAS #
247016-69-9
Chemical Name
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile Dihydrochloride
Chemical Formula
C15H18N6O.2HCl
Molecular Weight
371.27
Appearance
White Solid
Purity
98% by HPLC
Solubility
DMSO (~100 mM) or EtOH (~ 100 mM)
Storage Temp
-20°C
THERAPEUTIC AREA
Endocrinological Disorders
USE
Inhibition of dipeptidyl peptidase IV (DPP-IV) has been used to the treatment of type 2 diabetes
MDL NUMBER
MFCD12828773
CHEMACX
X1764022-5
INCHI
InChI=1S/C15H18N6O.2ClH/c16-8-12-3-4-14(20-10-12)19-6-5-18-11-15(22)21-7-1-2-13(21)9-17;;/h3-4,10,13,18H,1-2,5-7,11H2,(H,19,20);2*1H/t13-;;/m0../s1
SMILES
C1C[C@H](N(C1)C(=O)CNCCNC2=NC=C(C=C2)C#N)C#N.Cl.Cl
Peptide sequence
Not Applicable
RTECS
UY0282600
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Promo text for AGS discount
N/A
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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