Dynasore

SKU
D-2298
  • CAS:304448-55-3
  • Formula:C18H14N2O4
  • Appearance:Off-White Solid
  • Purity:98% by NMR
Product Name Qty
Dynasore
5 mg
$62.65
Dynasore
25 mg
$222.12
Cell-permeable. A reversible, noncompetitive inhibitor of dynamin that interferes in vitro with the GTPase activity of dynamin1, dynamin2, and Drp1, the mitochondrial dynamin, but not of other small GTPases. Dynasore acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation within seconds of dynasore addition.
More Information
Alternate Name/Synonyms
3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide
SKU
D-2298
CAS #
304448-55-3
Chemical Name
3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide
Chemical Formula
C18H14N2O4
Appearance
Off-White Solid
Purity
98% by NMR
Solubility
DMSO (10 mg/ml) or EtOH (1 mg/ml)
Melting Point
251.04 °C 
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Cell permeable dynamin inhibitor, that blocks endocytosis
MDL NUMBER
MFCD00292551
CHEMACX
X1598587-2
INCHI
InChI=1S/C18H14N2O4/c21-15-6-5-11(7-17(15)23)10-19-20-18(24)14-8-12-3-1-2-4-13(12)9-16(14)22/h1-10,21-23H,(H,20,24)/b19-10+
SMILES
c1ccc2cc(c(cc2c1)C(=O)N/N=C/c3ccc(c(c3)O)O)O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
UN 3077
PACKING GROUP
III
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
GHS PICTOGRAMS
Handling Protect from air and light
UN #'S UN 3077
Packing Group III
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