DZNep, Methyl transferase inhibitor
SKU
D-2639
- CAS:102052-95-9
- Formula:C12H14N4O3
- MW:262.26
- Appearance:Beige solid
- Purity:98% by HPLC NMR (Conforms)
SDS
CofA
DZNep (102052-95-9) is a potent histone methyltransferase inhibitor which decreases global histone methylation. Inhibits trimethylation of H3K27 and H4K20 in vitro. Selectively induces apoptosis in multiple cancer cell lines with no effect on normal cells. DZNep may be used in cocktails to chemically induce pluripotent stem cells (CiPSCs) from somatic cells. Enhances angiogenesis in a mouse model of limb ischemia.
More Information
Alternate Name/Synonyms
3-Deazaneplanocin A; NSC 617989
SKU
D-2639
CAS #
102052-95-9
Chemical Formula
C12H14N4O3
Molecular Weight
262.26
Appearance
Beige solid
Purity
98% by HPLC NMR (Conforms)
Solubility
Soluble in DMSO (up to 20 mg/ml)
Stability
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Storage Temp
-20°C (des.)
Hazard Image
Yes
Promo text for AGS discount
N/A