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Ebselen

SKU
E-3294
  • CAS:60940-34-3
  • Formula:C13H9NOSe
  • MW:274.2
  • Appearance:White Solid
  • Purity:98%
Product Name Qty
Ebselen
25 mg
$77.46
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An anti-inflammatory, anti-oxidant compound. Shown to be a neuroprotective agent and an inhibitor of free radical induced apoptosis.
More Information
Alternate Name/Synonyms
2-phenyl-1,2-benzisoselenazol-3(2H)-one
SKU
E-3294
CAS #
60940-34-3
Chemical Name
2-PHENYL-BENZO[D]ISOSELENAZOL-3-ONE
Chemical Formula
C13H9NOSe
Molecular Weight
274.2
Appearance
White Solid
Purity
98%
Solubility
Soluble in DMSO
Storage Temp
+4°C
THERAPEUTIC AREA
Neurological Disorders
USE
Ebselen is shown to inhibit the 5-lipoxygenase (5-LO) and 15-lipoxygenase (15-LO) enzymes in the absence of glutathione
MDL NUMBER
MFCD00210937
CHEMACX
X1035216-8
INCHI
InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
SMILES
c1ccc(cc1)n2c(=O)c3ccccc3[se]2
RTECS
DE4140750
PACKING GROUP
III
HAZARD CLASS
Class 6.1
Handling
Store in Tightly Sealed Vial
GHS PICTOGRAMS
Handling Store in Tightly Sealed Vial
Packing Group III
Citations Chronic alcohol feeding induces biochemical, histological, and functional alterations in rat retina
Ebselen prevents chronic alcohol-induced rat hippocampal stress and functional impairment
Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium
Caloric restriction controls stationary phase survival through Protein Kinase A (PKA) and cytosolic pH
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