Elastatinal, Elastase Inhibitor
- MW:512.56 Da
- Appearance:Yellow to off white powder
Starting at $78.19
Elastatinal is a tetrapeptide derivative with an aldehyde group which is essential for inhibitory activity such as pancreatic elastase. It is a much stronger inhibitor of elastase from pancreas than from leucocytes because it’s isolated from Actinomycetes.
Elastatinal is a highly specific inhibitor of elastase-like serine proteases. Elastatinal can also be used as an inhibitor for thermitase, a thermostable serine protease from Thermoactinomyces vulgaris, and for macroglobulin-protease complexes.
Elastatinal inhibits the proteolytic activity of poliovirus and rhinovirus 2A proteinases in vitro. Additionally, it has no effect on DNA repair and UV-induced sister chromatid exchanges, and inhibits the cleavages found at Ala-Ala bonds in peptides that represent the capsid/nucleocapsid site. Elastatinal is an irreversible inhibitor of neutrophil and rat microglia elastase.
• Used as a microbial product inhibitor for elastase
• Ability to reduce rate of degradation of endostain
• Used to effectively inhibit phenylmethylsulfonyl fluoride
• Ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro
• EC Number: 257-426-7
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Keep dry. Freeze upon arrival. Protect from light. Handle in accordance with good industrial hygiene and safety practice.|