Endotoxin Removal Affisorbent (Polymyxin B) (Agarose) 4B-CL

SKU
E-3353
  • Appearance:Liquid Suspension
Product Name Qty
Endotoxin Removal Affisorbent (Polymyxin B) (Agarose) 4B-CL
10 ml
$192.88

Applications:

Endotoxin Affisorbent consists of immobilized polymyxin B on 4B-CL. The polymyxins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymyxin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide. The immobilized polymixin B gel is a stable affinity matrix that resists leaching of ligand into the valuable preparation. Affisorbent Endotoxin Removing Gel can also be used to remove endotoxins from nucleic acid (DNA) samples.Polymyxin B-4B-CL is used in protein chromatography, affinity chromatography and specialty resins. Polymyxin B- 4B-CL has been used to study periodontitis and endodontic infections as well as obesity and type 2 diabetes. Polymyxin B- 4B-CL is also used for the removal of endotoxin levels in protein solutions, cell culture media, ascites.

 

Technical Specifications:

  • Ligand: Polymyxin B
  • Matrix: 4B-CL (crosslinked agarose beads, 4%)
  • Particle size range: 52 – 165 µm
  • Matrix activation: Cyanogen bromide
  • Attachment: Amino group
  • Binding capacity: 200 – 500 µg LPS from E. coli serotype 0128:B12
  • pH stability: 3 – 10
  • Supplied as slurry in 50% glycerol containing 0.02% sodium azide
  • Storage temp: 2 – 8 °C
More Information
SKU
E-3353
Appearance
Liquid Suspension
Storage Temp
4°C
Hazard Image
Yes
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