Epothilone A

SKU
E-2447
  • CAS:152044-53-6
  • Formula:C26H39NO6S
  • MW:493.7
  • Appearance:White to off white powder
  • Purity:>98% by HPLC
Product Name Qty
Epothilone A
0.1 mg
$349.58
Epothilone A
0.5 mg
$1,223.53
*Please inquire the availability for this product. Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol binding site, and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A has been investigated in clinical trials as an antitumor agent.
More Information
Alternate Name/Synonyms
EpoA
SKU
E-2447
CAS #
152044-53-6
Chemical Formula
C26H39NO6S
Molecular Weight
493.7
Appearance
White to off white powder
Purity
>98% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
The epothilones are a novel class of antineoplastic agents
MDL NUMBER
MFCD09970958
INCHI
InChI=1S/C26H39NO6S/c1-14-8-7-9-19-21(32-19)11-20(15(2)10-18-13-34-17(4)27-18)33-23(29)12-22(28)26(5,6)25(31)16(3)24(14)30/h10,13-14,16,19-22,24,28,30H,7-9,11-12H2,1-6H3/b15-10+/t14-,16+,19+,20-,21-,22-,24-/m1/s1
SMILES
Cc1nc(cs1)/C=C(\C)/[C@H]2C[C@@H]3[C@@H](O3)CCC[C@H]([C@H]([C@@H](C(=O)C([C@@H](CC(=O)O2)O)(C)C)C)O)C
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