Eprinomectin B1a

SKU
E-2457
  • CAS:133305-88-1
  • Formula:C50H75NO14
  • MW:914.1 Da
  • Appearance:White solid
  • Purity:>99% by HPLC
Product Name Qty
Eprinomectin B1a
1 mg
$349.58
Eprinomectin B1a
5 mg
$1,223.53

Description:

Eprinomectin B1a is a semi-synthetic analogue of avermectin B1a prepared by oxidation of the 4"-hydroxy moiety and reductive amination followed by acetylation. Eprinomectin B1a is the major component (>90%) of the commercial product for endo- and exo-parasite control, eprinomectin.

Members of the avermectin/milbemycin class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides and acaricides.

More Information
Alternate Name/Synonyms
Eprinomectin component B1a
SKU
E-2457
CAS #
133305-88-1
Chemical Name
N-[(2S,3R,4S,6S)-6-[(2S,3S,4S,6R)-6-[(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-butan-2-yl-21',24'-dihydroxy-3,11',13',22'-tetramethyl-2'-oxospiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22
Chemical Formula
C50H75NO14
Molecular Weight
914.1 Da
Appearance
White solid
Purity
>99% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO Poor water solubility
Storage Temp
-20°C
USE
A component in the control of parasites, arachnids and insects.
MDL NUMBER
MFCD00866565
INCHI
InChI=1S/C50H75NO14/c1-12-26(2)45-29(5)18-19-49(65-45)24-36-21-35(64-49)17-16-28(4)44(27(3)14-13-15-34-25-58-47-43(53)30(6)20-37(48(54)61-36)50(34,47)55)62-41-23-39(57-11)46(32(8)60-41)63-40-22-38(56-10)42(31(7)59-40)51-33(9)52/h13-16,18-20,26-27,29,31-32,35-47,53,55H,12,17,21-25H2,1-11H3,(H,51,52)/b14-13+,28-16+,34-15+/t26-,27-,29-,31-,32-,35?,36-,37-,38-,39-,40-,41-,42+,43+,44-,45?,46-,47+,49+,50+/m0/s1
SMILES
CC[C@H](C)C1[C@H](C=C[C@@]2(O1)C[C@@H]3CC(O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@@H]([C@@H](O7)C)NC(=O)C)OC)OC)\C)C
Handling
The product itself does not burn. If technically possible use local exhaust ventilation. No special provisions if the product is used appropriately.
GHS PICTOGRAMS
HandlingThe product itself does not burn. If technically possible use local exhaust ventilation. No special provisions if the product is used appropriately.
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