SDS
CofA
Description:
Eprinomectin B1b is a semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4"-hydroxy moiety and reductive amination followed by acetylation. Eprinomectin B1b is the minor component (<10%) of the commercial product for endo- and exo-parasite control, eprinomectin.
Members of the avermectin/milbemycin class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides and acaricides.
More Information
Alternate Name/Synonyms
Eprinomectin component B1b
SKU
E-2459
CAS #
13305-89-2
Chemical Formula
C49H73NO14
Molecular Weight
900.1 Da
Appearance
White solid
Purity
>99% by HPLC
Solubility
Soluble in DMSO, DMF, ethanol, methanol, and water (poor).
Storage Temp
-20°C
USE
A component in the control of parasites, arachnids and insects.
MDL NUMBER
MFCD00866563
INCHI
InChI=1S/C49H73NO14/c1-25(2)43-28(5)17-18-48(64-43)23-35-20-34(63-48)16-15-27(4)44(26(3)13-12-14-33-24-57-46-42(52)29(6)19-36(47(53)60-35)49(33,46)54)61-40-22-38(56-11)45(31(8)59-40)62-39-21-37(55-10)41(30(7)58-39)50-32(9)51/h12-15,17-19,25-26,28,30-31,34-46,52,54H,16,20-24H2,1-11H3,(H,50,51)/b13-12+,27-15+,33-14+/t26-,28-,30-,31-,34+,35-,36-,37-,38-,39-,40-,41+,42+,43+,44-,45-,46+,48+,49+/m0/s1
SMILES
C[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@@H]([C@@H](O6)C)NC(=O)C)OC)OC)\C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C(C)C)C)O
Handling
The product itself does not burn. If technically possible use local exhaust ventilation. No special provisions if the product is used appropriately.
| GHS PICTOGRAMS |    |
|---|---|
| Handling | The product itself does not burn. If technically possible use local exhaust ventilation. No special provisions if the product is used appropriately. |
