EPZ005687

SKU
E-2509
  • CAS:1396772-26-1
  • Formula:C32H37N5O3
  • MW:539.67
  • Appearance:white powder
  • Purity:≥99%
Product Name Qty
EPZ005687
1 mg
$44.00
EPZ005687
5 mg
$85.80
EPZ005687
25 mg
$286.00
EPZ005687
100 mg
$858.00

EPZ-005687 is a highly selective inhibitor of mutant EZH2, a histone methyltransferase (HMT) that exhibits point mutations at key residues Tyr641 and Ala677 in non-Hodgkin’s lymphoma and other cancers. EPZ-005687 displays anticancer chemotherapeutic activity through its inhibition of EZH2; this enzyme is responsible for methylation of lysine and arginine residues and controls gene transcription fidelity in cells. Inhibition of mutant EZH2 induces apoptosis.

More Information
Alternate Name/Synonyms
1-cyclopentyl-N-[(4, 6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[4-(morpholin-4-ylmethyl) phenyl]indazole-4-carboxamide
SKU
E-2509
CAS #
1396772-26-1
Chemical Formula
C32H37N5O3
Molecular Weight
539.67
Appearance
white powder
Purity
≥99%
Solubility
DMSO
Storage Temp
-20°C
Hazard Image
Yes
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