Ertapenem Sodium Salt

SKU
E-2497
  • CAS:153773-82-1
  • Formula:C22H24N3NaO7S
  • MW:497.5
  • Appearance:White to light yellow powder
  • Purity:>97%
Product Name Qty
Ertapenem Sodium Salt
5 g
$521.51
Ertapenem Sodium Salt
25 g
$1,798.83
Ertapenem Sodium Salt
1 g
$134.01

Desciription

Ertapenem is a new carbapenem which has β-Lactam features and is regarded as having the most potent and the widest spectrum of antimicrobial activity, like imipenem and meropenem. It is effective against both Gram-negative and Gram-positive aerobes and anaerobes and is resistant to nearly all beta-lactamases, including extended-spectrum Beta-lactamases and AmpCs.

Ertapenem has a mechanism that suppresses synthesis of bacterial cell walls. The drug binds to penicillin binding proteins (PBPs), especially PBPs 2 and 3, on bacterial cell walls and inhibits the synthesis of peptidoglycan by interfering the final transpeptidation step.

This antibiotic is approved in the US and the EU as a parenteral infection treatment. It is used for intra-abdominal infection, complicated skin and soft-tissue infections,  community-acquired pneumonia and acute pelvic infection.

 

Applications

• Antibiotic

• Used to treat inflammatory diseases

 

References

“Ertapenem”

“Ertapenem, the first of a new group of carbapenems”

“Ertapenem: review of a new carbapenem”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
ertapenem monosodium; 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-carboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)-; sodium (4R,5S,6S)-3-({(3S,5S)-5-[(3-carboxylatophenyl)carbamoyl]pyrrolidinium-3-yl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; MK 826
SKU
E-2497
CAS #
153773-82-1
Chemical Name
sodium;(4R,5S,6S)-3-[(3S,5S)-5-[(3-carboxylatophenyl)carbamoyl]pyrrolidin-1-ium-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
Chemical Formula
C22H24N3NaO7S
Molecular Weight
497.5
Appearance
White to light yellow powder
Purity
>97%
Solubility
Soluble in water
Storage Temp
2-8℃
THERAPEUTIC AREA
Complicated Intra-Abdominal Infections, Community Acquired Pneumonia and Urinary Tract Infections Including Pyelonephritis
USE
A potent and the most widest spectrum of antibiotic
Handling
Use in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.
Certificate of Analysis 1
Certificate of Analysis 2
GHS PICTOGRAMS
HandlingUse in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.
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