Erythromycin B

SKU
E-2471
  • CAS:527-75-3
  • Formula:C37H67NO12
  • MW:717.9 Da
  • Appearance:White solid
  • Purity:>98% by HPLC
Product Name Qty
Erythromycin B
5 mg
$498.78
Erythromycin B
1 mg
$162.18

Description

Erythromycin B (12-deoxyerythromycin) is a minor co-metabolite of erythromycin produced Saccharopolyspora erythreae. Erythromycin B exhibits broad spectrum antibiotic activity, albeit less potent than erythromycin A. Erythromycin B played an integral part of the SAR studies of semi-synthetic erythromycins, however none reached clinical development.

 

More Information
Alternate Name/Synonyms
12-Deoxyerythromycin; Berythromycin; Beritromicina; Berythromycine; Berythromycinum
SKU
E-2471
CAS #
527-75-3
Chemical Name
(3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
Chemical Formula
C37H67NO12
Molecular Weight
717.9 Da
Appearance
White solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
A minor co-metabolite that exhibits broad spectrum antibiotic activity
MDL NUMBER
MFCD01729130
INCHI
InChI=1S/C37H67NO12/c1-14-26-20(4)29(40)21(5)28(39)18(2)16-36(9,44)33(50-35-30(41)25(38(11)12)15-19(3)46-35)22(6)31(23(7)34(43)48-26)49-27-17-37(10,45-13)32(42)24(8)47-27/h18-27,29-33,35,40-42,44H,14-17H2,1-13H3/t18-,19-,20+,21+,22+,23-,24+,25+,26-,27+,29+,30-,31+,32+,33-,35+,36-,37-/m1/s1
SMILES
CC[C@@H]1[C@@H]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)C
Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
GHS PICTOGRAMS
HandlingAvoid contact with skin and eyes. Avoid formation of dust and aerosols.
We found other products you might like!
To Top