Etoposide (100 mM) Solution

SKU

E-2308

CAS:33419-42-0
Formula:C₂₂H₂₉FO₅
MW:588.56
Appearance:Liquid
Purity:98% by HPLC

SDS

CofA

Product Name	Qty
Etoposide (100 mM) Solution 100 µl $87.39

Details

A topoisomerase II inhibitor. A derivative of podophyllotoxin that has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in human T cells, mouse thymocytes, and HL-60 human leukemia cells

Specifications

More Information

Alternate Name/Synonyms

4-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-D-glucopyranoside, VP-16-213

SKU

E-2308

CAS #

33419-42-0

Chemical Name

4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside, VP-16-213

Chemical Formula

C₂₂H₂₉FO₅

Molecular Weight

588.56

Appearance

Liquid

Purity

98% by HPLC

Melting Point

236-251 °C

Storage Temp

-20°C

THERAPEUTIC AREA

Oncological Disorders

USE

Inhibits DNA synthesis via topoisomerase II inhibition used as a form of chemotherapy for cancers

MDL NUMBER

MFCD00869325

CHEMACX

X1004425-4

INCHI

InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1

SMILES

C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@@H]3c4cc5c(cc4[C@H]([C@@H]6[C@@H]3COC6=O)c7cc(c(c(c7)OC)O)OC)OCO5)O)O

Peptide sequence

Not Applicable

RTECS

KC0190000

UN #'S

Not Applicable

PACKING GROUP

Not Applicable

HAZARD CLASS

Not Applicable