Etoposide (100 mM) Solution
SKU
E-2308
- CAS:33419-42-0
- Formula:C22H29FO5
- MW:588.56
- Appearance:Liquid
- Purity:98% by HPLC
SDS
CofA
A topoisomerase II inhibitor. A derivative of podophyllotoxin that has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in human T cells, mouse thymocytes, and HL-60 human leukemia cells
More Information
Alternate Name/Synonyms
4-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-D-glucopyranoside, VP-16-213
SKU
E-2308
CAS #
33419-42-0
Chemical Name
4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside, VP-16-213
Chemical Formula
C22H29FO5
Molecular Weight
588.56
Appearance
Liquid
Purity
98% by HPLC
Melting Point
236-251 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Inhibits DNA synthesis via topoisomerase II inhibition used as a form of chemotherapy for cancers
MDL NUMBER
MFCD00869325
CHEMACX
X1004425-4
INCHI
InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
SMILES
C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@@H]3c4cc5c(cc4[C@H]([C@@H]6[C@@H]3COC6=O)c7cc(c(c(c7)OC)O)OC)OCO5)O)O
Peptide sequence
Not Applicable
RTECS
KC0190000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
| GHS PICTOGRAMS |
|
|---|---|
| Handling | Protect from light and moisture |
| UN #'S | Not Applicable |
| Packing Group | Not Applicable |