Everolimus

SKU
E-2309
  • CAS:159351-69-6
  • Formula:C53H83NO14
  • MW:958.22
  • Appearance:Off-White Solid
  • Purity:98% by HPLC
Product Name Qty
Everolimus
5 mg
$131.00
Everolimus
25 mg
$495.50
A derivative of the macrolide Rapamycin (Cat. No. 1568-5, 50) that acts as an immunosuppressant, mTOR inhibitor and anticancer agent. It targets the raptor mammalian target of rapamycin (mTORC1).
More Information
Alternate Name/Synonyms
RAD-001
SKU
E-2309
CAS #
159351-69-6
Chemical Name
40-O-(2-HYDROXYETHYL)-RAPAMYCIN
Chemical Formula
C53H83NO14
Molecular Weight
958.22
Appearance
Off-White Solid
Purity
98% by HPLC
Solubility
DMSO
Melting Point
110-115 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Autoimmune Diseases
USE
It is used as an immunosuppressant to prevent rejection of organ transplants
MDL NUMBER
MFCD00929329
CHEMACX
X1495513-8
INCHI
InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35+,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
SMILES
C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC
Peptide sequence
Not Applicable
RTECS
VE6255000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and air
GHS PICTOGRAMS
HandlingProtect from light and air
UN #'SNot Applicable
Packing GroupNot Applicable
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